Studies: Huntington, Crohn’s, Eggs, and Aging

Vol. 10

Eating Schedule and Huntington Disease

Huntington disease (HD) is an inherited progressive disease that can cause involuntary movements and psychological problems. Symptoms of HD appear in adulthood and worsen over time. Children with at least one parent with HD have a 50% chance of developing HD. As of now, HD is thought to be caused by the buildup of mutant huntingtin protein (mHTT) and there is no known cure. HD is linked to a problem with autophagy (cell death). The University of British Columbia (UBC) published research involving a mouse model of HD. Mice were restricted to a 6 hour eating windown, which prompted autophagy in the mice. There are practical applications for humans utilizing intermittent fasting, or a fasting mimetic diet.

https://goo.gl/wZNs8x

 

Eggs and Infants

Eggs. They are good for you, this much is made more and more obvious every day. Recently though, the Brown School at Washington University in St. Louis, published research stating that eggs are beneficial for infants as well.

Starting at 6 months of age, infants were fed eggs (whole eggs) as part of their diet. The infants, aged 6-9 months, were fed 1 egg per day. Eggs, being high in choline precursors, DHA, vitamins A, B12, selenium and other fatty acids, are vital for brain development.

https://goo.gl/QoNTZd

 

Artificial Sweeteners and Crohn’s

Researchers at Case Western Reserve University found artificial sweeteners (splenda, maltodextrin, and sucralose) worsened the symptoms of people with Crohn’s disease. Accorfding to the research, the artificial sweeteners increased the presence of proteobacteria and myeloperoxidase. Both of these are involved in inflammatory and autoimmune responses in people with Crohn’s. Researchers did not find the same reaction in people that do not suffer from Crohn’s.

https://goo.gl/HMuTPs

 

Exercise Slows Aging

Yet another reason to regularly exercise. The University of Birmingham and Kings College, London conducted research regarding exercise and aging. The study consisted of 125 participants, aged 55-79, 84 males and 41 females. Excluded from the study were smokers, heavy drinkers, and those who had high blood pressure. A control group of 75 non-exercisers was measured as well. The treatment group, the exercisers, had no loss of muscle mass or strength, no increase in body fat or cholesterol and their testosterone levels remained stable. The immune systems of the exercisers was also comparable to a younger person. One reason for this, according to the researchers, was that exercise prevented the shrinking of the thymus, which normally begins around age 20.

https://goo.gl/AfRLa5

 

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How the gut influences neurologic disease

A study sheds new light on the connection between the gut and the brain, untangling the complex interplay that allows the byproducts of microorganisms living in the gut to influence the progression of neurodegenerative diseases.

Source: How the gut influences neurologic disease: Researchers are identifying the key players involved in the gut-brain connection and their role in disease progression — ScienceDaily

Sugars in infant formulas pose risk to babies with inherited metabolic disorder

Babies with inherited intolerance of fructose face a risk of acute liver failure if they are fed certain widely available formulas containing fructose, pediatricians and geneticists are warning. Baby formula manufacturers should remove fructose or sucrose, or explicitly label their products to allow parents to avoid those sweeteners if necessary, the doctors say.

Source: Sugars in infant formulas pose risk to babies with inherited metabolic disorder: Acute liver failure caused by hereditary fructose intolerance — ScienceDaily

New link between gut microbiome and artery hardening discovered

The level of diversity of the ‘good bacteria’ in our digestive systems has been found to be linked to a feature of cardiovascular disease — hardening of the arteries — in new research.

Source: New link between gut microbiome and artery hardening discovered — ScienceDaily

A gut bacterium’s guide to building a microbiome

Many studies have linked the gut microbiome to health and disease. New research reveals mechanisms utilized by gut bacteria to assemble a microbiome in the first place.

Source: A gut bacterium’s guide to building a microbiome: Unlike invading pathogens, which are attacked by the immune system, certain good bacteria in the gut invite an immune response in order to establish robust gut colonization — ScienceDaily

The Many Benefits of Sauna Use

While not exactly a new thing, using the sauna has been shown somewhat recently to have tremendous health benefits. More and more quality research is coming out demonstrating that regular sauna use is so beneficial for people in so many ways.

 

Then and Now

Sauna is a Finnish word referring to the traditional Finnish bath and/or bathhouse itself. A sauna as thought of today, is originated in Finland. A modern sauna is usually a simple, wooden room, with varying heat sources in the center. The most common heat source is an electric heater, filled with rocks. The way a sauna achieves such high temperatures without harming people is by controlling the humidity and air flow.The lower humidity in saunas compared to steam rooms is what allows for higher temperatures.

 

Benefits

There are many benefits of regular sauna use. Let’s dive right in.

Circulation

  • Heat causes increased blood flow
  • Oxygenation of cells, organs, and tissue
  • Mitochondrial boost
  • Metabolic waste flushing
  • Improved blood pressure
  • Elevated heart rate

 

Performance

  • Elevated heart rate: As mentioned above a sauna session will elevate heart rate to a level similar to medium intensity exercise
  • Increased levels of IGF-1: Some studies have shown increases by as much as 200%-330%! IGF-1 is a hormone that causes anabolism (muscle growth), and recovery from exercise. Both leading to increased muscle growth
  • Increased insulin sensitivity: Great for overall health and muscle growth
  • Increase in heat shock proteins(HSP): Also aids in muscle growth by preventing catabolism (muscle breakdown) and increasing MPS (muscle protein synthesis)
  • Reduces DOMS (delayed onset muscle soreness)

 

Overall health/longevity

  • 48% lower risk of heart disease
  • Increased insulin sensitivity: Insulin resistance/poor insulin sensitivity is a common factor in many metabolic disorders
  • Increase in FOXO3: Gene associated with longevity and protects against DNA damage
  • Heart rate increase: Regular elevation of heart rate increases heart health
  • Heat Shock Proteins: HSP activate FOXO3 which help to prevent heart, brain, and metabolic disorders. HSP also increase lifespan and are associated with centenarians
  • Lower levels of stress
  • Increases in attention and memory
  • Myelin growth: Myelin is the sheath around nerve cells facilitating signal transmission
  • Neurogenesis: Growth of new brain cells
  • 24% or 40% (depending on frequency) reduction in all cause mortality
  • 27% or 50% (depending on frequency) reduction in cardiovascular death
  • Up to 65% reduction in Alzheimer’s and/or dementia (depending on frequency)
health benefits of sauna use
Inside a sauna

Infrared Sauna

As this technology is somewhat new, less data is available. What has been observed thus far is that full spectrum ( as opposed to only mid or near spectrum) offers the most benefits. Infrared saunas are preferred more and more as there is less heat, so they are more bearable to some. Similar to more traditional saunas, infrared saunas can provide the following benefits:

  • Detox
  • Lowered blood pressure
  • Mood enhancement
  • Similar circulation benefits
  • Cell health
  • Wound healing
  • Oxygenation

 

How Much and How Often

Is probably what you want to know now. Most of the data shows that benefits start at a frequency of 2-3 sessions a week, but more robust benefits are observed at a frequency of 4-7 sessions per week. As far as duration and temperature, that hasn’t been determined exactly, but a sweet spot seems to be about 174 degrees Fahrenheit for about 20 minutes.

 

 

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Eggs not linked to cardiovascular risk, despite conflicting advice: No extra risk for people with pre-diabetes or type 2 diabetes

Eating up to 12 eggs a week does not increase cardiovascular risk factors in people with pre-diabetes or type 2 diabetes, new research finds — despite conflicting dietary advice continuing around the world.

Source: Eggs not linked to cardiovascular risk, despite conflicting advice: No extra risk for people with pre-diabetes or type 2 diabetes — ScienceDaily